Integrative GLP-1: Adjuncts and Muscle-Preservation for 2026

GLP-1s work — but integrative and functional physicians add the layers that make the results durable and healthy.

Published March 19, 2026 · 5 min read · Back to Health & Wellness Doctors

Protect lean mass

Resistance-training prescription, adequate protein (1.2–1.6 g/kg), and creatine. Consider CJC/ipamorelin or MK-677 (physician-supervised) in patients losing lean mass rapidly.

Handle GI and adherence

BPC-157 for GI tolerance, glutamine, and slow titration. Track waist circumference and body composition, not just weight, every 6–8 weeks.

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